The expansion of slum areas have been one of the critical challenges manifested with the rapid urbanization of the global south countries.As one of the metropolitan cities in Ethiopia, Gondar city experienced this problem for long time.This study aimed at investigating the adversities related to physical environment, means of survival, health situa
Effects of Adding Silica Fume and Empty Fruit Bunch to the Mix of Cement Brick
Silica fume (SF) and palm oil empty fruit bunch (EFB) are the by-products of the ferroalloy smelting industry and oil palm plantation, which require proper disposal to minimize SuperX the environmental impacts.To consume the by-products, the feasibility of utilizing SF and EFB to fabricate bricks was studied.Limited studies were adopting EFB as the
Inhibiting Type VI Secretion System Activity with a Biomimetic Peptide Designed To Target the Baseplate Wedge Complex
ABSTRACT Human health is threatened by bacterial infections that are increasingly resistant to multiple drugs.A recently emerged strategy consists of disarming pathogenic bacteria by targeting and blocking their virulence factors.The type VI secretion system (T6SS) is a widespread secretion nanomachine encoded and employed by pathogenic strains to
Biophysical induction of vascular smooth muscle cell podosomes.
Vascular smooth muscle cell (VSMC) migration and matrix degradation occurs with intimal hyperplasia associated with atherosclerosis, vascular injury, and restenosis.One proposed mechanism Skin Conditions by which VSMCs degrade matrix is through the use of podosomes, transient actin-based structures that are thought to play a role in extracellular m
CRISPR/Cas9 for hepatitis B virus infection treatment
Abstract Hepatitis B virus (HBV) infection remains a Transfer Aides global health challenge.Despite the availability of effective preventive vaccines, millions of people are at risk of cirrhosis and hepatocellular carcinoma.Current drug therapies inhibit viral replication, slow the progression of liver fibrosis and reduce infectivity, but they rare